Stearoyl-CoA desaturase 1 expression is downregulated in liver and udder during E. coli mastitis through enhanced expression of repressive C/EBP factors and reduced expression of the inducer SREBP1A

BACKGROUND: Stearoyl-CoA desaturase 1 (SCD1) desaturates long chain fatty acids and is therefore a key enzyme in fat catabolism. Its synthesis is downregulated in liver during illnesses caused by high levels of circulating lipopolysaccharide (LPS). SCD1 expression is known to be stimulated under adi...

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Detalles Bibliográficos
Autores principales: Xu, Tianle, Shen, Xiangzhen, Seyfert, Hans-Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955114/
https://www.ncbi.nlm.nih.gov/pubmed/27439381
http://dx.doi.org/10.1186/s12867-016-0069-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955114/
https://www.ncbi.nlm.nih.gov/pubmed/27439381
http://dx.doi.org/10.1186/s12867-016-0069-5

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