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Prognostic significance of FOXM1 expression and antitumor effect of FOXM1 inhibition in synovial sarcomas

BACKGROUND: Synovial sarcoma (SS) is a soft tissue sarcoma of unknown histogenesis. Most metastatic or unresectable cases are incurable. Novel antitumor agents and precise prognostication are needed for SS patients. The protein forkhead box M1 (FOXM1), which belongs to the FOX family of transcriptio...

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Detalles Bibliográficos
Autores principales: Maekawa, Akira, Kohashi, Kenichi, Kuda, Masaaki, Iura, Kunio, Ishii, Takeaki, Endo, Makoto, Nakatsura, Tetsuya, Iwamoto, Yukihide, Oda, Yoshinao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955131/
https://www.ncbi.nlm.nih.gov/pubmed/27439614
http://dx.doi.org/10.1186/s12885-016-2542-4