Cargando…

Virtual screening and experimental validation of novel histone deacetylase inhibitors

BACKGROUND: Histone deacetylases (HDACs) are promising therapeutic targets for the treatment of cancer, diabetes and other human diseases. HDAC inhibitors, as a new class of potential therapeutic agents, have attracted a great deal of interest for both research and clinical applications. Increasing...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Yan-xin, Zhao, Jian, Song, Qiu-hang, Zheng, Li-hua, Fan, Cong, Liu, Ting-ting, Bao, Yong-li, Sun, Lu-guo, Zhang, Li-biao, Li, Yu-xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955146/
https://www.ncbi.nlm.nih.gov/pubmed/27443303
http://dx.doi.org/10.1186/s40360-016-0075-8