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The promising role of poly(ADP-ribose) polymerase inhibitors in prostate cancer
The TOPARP study showed the beneficial utility of olaparib in a heavily pretreated population of metastatic castration-resistant prostate cancer who were biomarker-positive for aberrations in DNA repair gene. A higher response rate to olaparib of 88% (14 out of 16 patients), time to radiographic pro...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Medknow Publications & Media Pvt Ltd
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955184/ https://www.ncbi.nlm.nih.gov/pubmed/26908063 http://dx.doi.org/10.4103/1008-682X.172821 |