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Tasquinimod modulates tumor-infiltrating myeloid cells and improves the antitumor immune response to PD-L1 blockade in bladder cancer

The infiltration of myeloid cells helps tumors to overcome immune surveillance and imparts resistance to cancer immunotherapy. Thus, strategies to modulate the effects of these immune cells may offer a potential therapeutic benefit. We report here that tasquinimod, a novel immunotherapy which target...

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Detalles Bibliográficos
Autores principales: Nakhlé, Jessica, Pierron, Valérie, Bauchet, Anne-Laure, Plas, Pascale, Thiongane, Amath, Meyer-Losic, Florence, Schmidlin, Fabien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955379/
https://www.ncbi.nlm.nih.gov/pubmed/27471612
http://dx.doi.org/10.1080/2162402X.2016.1145333