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A meta-analysis and systematic review of the prevalence of mitochondrially encoded 12S RNA in the general population: Is there a role for screening neonates requiring aminoglycosides?

BACKGROUND: This was a meta-analysis and systematic review to determine the global prevalence of the mitochondrially encoded 12S RNA (MT-RNR1) genetic mutation in order to assess the need for neonatal screening prior to aminoglycoside therapy. MATERIALS AND METHODS: A comprehensive search of MEDLINE...

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Detalles Bibliográficos
Autores principales: Ibekwe, Titus S., Bhimrao, Sanjiv K., Westerberg, Brian D., Kozak, Frederick K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955414/
https://www.ncbi.nlm.nih.gov/pubmed/26168747
http://dx.doi.org/10.4103/0189-6725.160342