Pyrin Inflammasome Activation and RhoA Signaling in the Autoinflammatory Diseases FMF and HIDS

Mutations of pyrin and mevalonate kinase (MVK) cause distinct interleukin-1β (IL-1β)-mediated autoinflammatory diseases, familial Mediterranean fever (FMF) and hyperimmunoglobulinemia D syndrome (HIDS). Pyrin forms an inflammasome when mutated or in response to bacterial modification of the GTPase R...

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Detalles Bibliográficos
Autores principales: Park, Yong Hwan, Wood, Geryl, Kastner, Daniel L., Chae, Jae Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955684/
https://www.ncbi.nlm.nih.gov/pubmed/27270401
http://dx.doi.org/10.1038/ni.3457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955684/
https://www.ncbi.nlm.nih.gov/pubmed/27270401
http://dx.doi.org/10.1038/ni.3457

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