Loss of protein association causes cardiolipin degradation in Barth syndrome

Cardiolipin is a specific mitochondrial phospholipid that has a high affinity for proteins and that stabilizes the assembly of supercomplexes involved in oxidative phosphorylation. We found that sequestration of cardiolipin in protein complexes is critical to protect it from degradation. The turnove...

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Detalles Bibliográficos
Autores principales: Xu, Yang, Phoon, Colin K.L., Berno, Bob, D’Souza, Kenneth, Hoedt, Esthelle, Zhang, Guoan, Neubert, Thomas A., Epand, Richard M., Ren, Mindong, Schlame, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955704/
https://www.ncbi.nlm.nih.gov/pubmed/27348092
http://dx.doi.org/10.1038/nchembio.2113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955704/
https://www.ncbi.nlm.nih.gov/pubmed/27348092
http://dx.doi.org/10.1038/nchembio.2113

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