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Specialized proteasome subunits play an essential role in thymic selection of CD8(+) T cells
The cells that stimulate positive selection express different specialized proteasome β-subunits than all other cells, including those involved in negative selection. Mice that lack all four specialized proteasome β-subunits, and therefore express only constitutive proteasomes in all cells, had a pro...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955723/ https://www.ncbi.nlm.nih.gov/pubmed/27294792 http://dx.doi.org/10.1038/ni.3480 |