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A cell-permeant peptide corresponding to the cUBP domain of USP5 reverses inflammatory and neuropathic pain

BACKGROUND: Cav3.2 T-type calcium currents in primary afferents are enhanced in various painful pathological conditions, whereas inhibiting Cav3.2 activity or expression offers a strategy for combating the development of pain hypersensitivity. We have shown that Cav3.2 channel surface density is str...

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Detalles Bibliográficos
Autores principales: Garcia-Caballero, Agustin, Gadotti, Vinicius M, Chen, Lina, Zamponi, Gerald W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955966/
https://www.ncbi.nlm.nih.gov/pubmed/27130589
http://dx.doi.org/10.1177/1744806916642444