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Gestational Diabetes Mellitus From Inactivation of Prolactin Receptor and MafB in Islet β-Cells

β-Cell proliferation and expansion during pregnancy are crucial for maintaining euglycemia in response to increased metabolic demands placed on the mother. Prolactin and placental lactogen signal through the prolactin receptor (PRLR) and contribute to adaptive β-cell responses in pregnancy; however,...

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Detalles Bibliográficos
Autores principales: Banerjee, Ronadip R., Cyphert, Holly A., Walker, Emily M., Chakravarthy, Harini, Peiris, Heshan, Gu, Xueying, Liu, Yinghua, Conrad, Elizabeth, Goodrich, Lisa, Stein, Roland W., Kim, Seung K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955982/
https://www.ncbi.nlm.nih.gov/pubmed/27217483
http://dx.doi.org/10.2337/db15-1527