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Gestational Diabetes Mellitus From Inactivation of Prolactin Receptor and MafB in Islet β-Cells
β-Cell proliferation and expansion during pregnancy are crucial for maintaining euglycemia in response to increased metabolic demands placed on the mother. Prolactin and placental lactogen signal through the prolactin receptor (PRLR) and contribute to adaptive β-cell responses in pregnancy; however,...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955982/ https://www.ncbi.nlm.nih.gov/pubmed/27217483 http://dx.doi.org/10.2337/db15-1527 |