AMPK Activation by Metformin Suppresses Abnormal Extracellular Matrix Remodeling in Adipose Tissue and Ameliorates Insulin Resistance in Obesity

Fibrosis is emerging as a hallmark of metabolically dysregulated white adipose tissue (WAT) in obesity. Although adipose tissue fibrosis impairs adipocyte plasticity, little is known about how aberrant extracellular matrix (ECM) remodeling of WAT is initiated during the development of obesity. Here...

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Detalles Bibliográficos
Autores principales: Luo, Ting, Nocon, Allison, Fry, Jessica, Sherban, Alex, Rui, Xianliang, Jiang, Bingbing, Xu, X. Julia, Han, Jingyan, Yan, Yun, Yang, Qin, Li, Qifu, Zang, Mengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955985/
https://www.ncbi.nlm.nih.gov/pubmed/27207538
http://dx.doi.org/10.2337/db15-1122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955985/
https://www.ncbi.nlm.nih.gov/pubmed/27207538
http://dx.doi.org/10.2337/db15-1122

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