Human Type 1 Diabetes Is Characterized by an Early, Marked, Sustained, and Islet-Selective Loss of Sympathetic Nerves

In humans, the glucagon response to moderate-to-marked insulin-induced hypoglycemia (IIH) is largely mediated by the autonomic nervous system. Because this glucagon response is impaired early in type 1 diabetes, we sought to determine if these patients, like animal models of autoimmune diabetes, hav...

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Detalles Bibliográficos
Autores principales: Mundinger, Thomas O., Mei, Qi, Foulis, Alan K., Fligner, Corinne L., Hull, Rebecca L., Taborsky, Gerald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955989/
https://www.ncbi.nlm.nih.gov/pubmed/27207540
http://dx.doi.org/10.2337/db16-0284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955989/
https://www.ncbi.nlm.nih.gov/pubmed/27207540
http://dx.doi.org/10.2337/db16-0284

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