Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet–Induced Insulin Resistance

In the current study, we used muscle-specific TRIB3 overexpressing (MOE) and knockout (MKO) mice to determine whether TRIB3 mediates glucose-induced insulin resistance in diabetes and whether alterations in TRIB3 expression as a function of nutrient availability have a regulatory role in metabolism....

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Wu, Mengrui, Kim, Teayoun, Jariwala, Ravi H., Garvey, W. John, Luo, Nanlan, Kang, Minsung, Ma, Elizabeth, Tian, Ling, Steverson, Dennis, Yang, Qinglin, Fu, Yuchang, Garvey, W. Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955990/
https://www.ncbi.nlm.nih.gov/pubmed/27207527
http://dx.doi.org/10.2337/db16-0154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955990/
https://www.ncbi.nlm.nih.gov/pubmed/27207527
http://dx.doi.org/10.2337/db16-0154

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