Cargando…

Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet–Induced Insulin Resistance

In the current study, we used muscle-specific TRIB3 overexpressing (MOE) and knockout (MKO) mice to determine whether TRIB3 mediates glucose-induced insulin resistance in diabetes and whether alterations in TRIB3 expression as a function of nutrient availability have a regulatory role in metabolism....

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Wei, Wu, Mengrui, Kim, Teayoun, Jariwala, Ravi H., Garvey, W. John, Luo, Nanlan, Kang, Minsung, Ma, Elizabeth, Tian, Ling, Steverson, Dennis, Yang, Qinglin, Fu, Yuchang, Garvey, W. Timothy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2016
Materias:	Pathophysiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955990/ https://www.ncbi.nlm.nih.gov/pubmed/27207527 http://dx.doi.org/10.2337/db16-0154

Ejemplares similares

TRIB3 Mediates Glucose-Induced Insulin Resistance via a Mechanism That Requires the Hexosamine Biosynthetic Pathway
por: Zhang, Wei, et al.
Publicado: (2013)

Endothelial Fcγ Receptor IIB Activation Blunts Insulin Delivery to Skeletal Muscle to Cause Insulin Resistance in Mice
por: Tanigaki, Keiji, et al.
Publicado: (2016)

Proinflammatory cytokine production and insulin sensitivity regulated by overexpression of resistin in 3T3-L1 adipocytes
por: Fu, Yuchang, et al.
Publicado: (2006)

Interactions Among Glucose Delivery, Transport, and Phosphorylation That Underlie Skeletal Muscle Insulin Resistance in Obesity and Type 2 Diabetes: Studies With Dynamic PET Imaging
por: Goodpaster, Bret H., et al.
Publicado: (2014)

Expression of Human Chemerin Induces Insulin Resistance in the Skeletal Muscle but Does Not Affect Weight, Lipid Levels, and Atherosclerosis in LDL Receptor Knockout Mice on High-Fat Diet
por: Becker, Melanie, et al.
Publicado: (2010)

Macrophage Adiponectin Expression Improves Insulin Sensitivity and Protects Against Inflammation and Atherosclerosis
por: Luo, Nanlan, et al.
Publicado: (2010)

Xenin-25 Amplifies GIP-Mediated Insulin Secretion in Humans With Normal and Impaired Glucose Tolerance but Not Type 2 Diabetes
por: Wice, Burton M., et al.
Publicado: (2012)

Altered Skeletal Muscle Lipase Expression and Activity Contribute to Insulin Resistance in Humans
por: Badin, Pierre-Marie, et al.
Publicado: (2011)

Renal Denervation Reverses Hepatic Insulin Resistance Induced by High-Fat Diet
por: Iyer, Malini S., et al.
Publicado: (2016)

Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?
por: Amati, Francesca, et al.
Publicado: (2011)

Brain Insulin Action Regulates Hypothalamic Glucose Sensing and the Counterregulatory Response to Hypoglycemia
por: Diggs-Andrews, Kelly A., et al.
Publicado: (2010)

Developmental Programming by Maternal Insulin Resistance: Hyperinsulinemia, Glucose Intolerance, and Dysregulated Lipid Metabolism in Male Offspring of Insulin-Resistant Mice
por: Isganaitis, Elvira, et al.
Publicado: (2014)

Hepatic fat and glucose tolerance in women with recent gestational diabetes
por: Mehmood, Sadia, et al.
Publicado: (2018)

Differential Expression of Novel Adiponectin Receptor-1 Transcripts in Skeletal Muscle of Subjects With Normal Glucose Tolerance and Type 2 Diabetes
por: Ashwal, Reut, et al.
Publicado: (2011)

Increased Lipolysis, Diminished Adipose Tissue Insulin Sensitivity, and Impaired β-Cell Function Relative to Adipose Tissue Insulin Sensitivity in Obese Youth With Impaired Glucose Tolerance
por: Kim, Joon Young, et al.
Publicado: (2017)

The Role of Endogenous Incretin Secretion as Amplifier of Glucose-Stimulated Insulin Secretion in Healthy Subjects and Patients With Type 2 Diabetes
por: Woerle, Hans Juergen, et al.
Publicado: (2012)

Portal Vein Glucose Sensors Do Not Play a Major Role in Modulating Physiological Responses to Insulin-Induced Hypoglycemia in Humans
por: Rossetti, Paolo, et al.
Publicado: (2009)

IGF-I Bioactivity in an Elderly Population: Relation to Insulin Sensitivity, Insulin Levels, and the Metabolic Syndrome
por: Brugts, Michael P., et al.
Publicado: (2010)

Tribbles Homolog 3 Mediates the Development and Progression of Diabetic Retinopathy
por: Pitale, Priyamvada M., et al.
Publicado: (2021)

Na(+)-d-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion
por: Gorboulev, Valentin, et al.
Publicado: (2012)

Distinct β-Cell Defects in Impaired Fasting Glucose and Impaired Glucose Tolerance
por: Kanat, Mustafa, et al.
Publicado: (2012)

SGLT2 Deletion Improves Glucose Homeostasis and Preserves Pancreatic β-Cell Function
por: Jurczak, Michael J., et al.
Publicado: (2011)

Glucagon-Like Peptide 1 Recruits Muscle Microvasculature and Improves Insulin’s Metabolic Action in the Presence of Insulin Resistance
por: Chai, Weidong, et al.
Publicado: (2014)

The Insulin-Like Growth Factor-1 Receptor Is a Negative Regulator of Nitric Oxide Bioavailability and Insulin Sensitivity in the Endothelium
por: Abbas, Afroze, et al.
Publicado: (2011)

Angiotensin II Reduces Mitochondrial Content in Skeletal Muscle and Affects Glycemic Control
por: Mitsuishi, Masanori, et al.
Publicado: (2009)

Perivascular Adipose Tissue Control of Insulin-Induced Vasoreactivity in Muscle Is Impaired in db/db Mice
por: Meijer, Rick I., et al.
Publicado: (2013)

CD14 Modulates Inflammation-Driven Insulin Resistance
por: Fernández-Real, José Manuel, et al.
Publicado: (2011)

Natural History of Insulin Sensitivity and Insulin Secretion in the Progression From Normal Glucose Tolerance to Impaired Fasting Glycemia and Impaired Glucose Tolerance: The Inter99 Study
por: Færch, Kristine, et al.
Publicado: (2009)

Short-Term Caloric Restriction Normalizes Hypothalamic Neuronal Responsiveness to Glucose Ingestion in Patients With Type 2 Diabetes
por: Teeuwisse, Wouter M., et al.
Publicado: (2012)

Effect of Endothelium-Specific Insulin Resistance on Endothelial Function In Vivo
por: Duncan, Edward R., et al.
Publicado: (2008)

Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver
por: Jelenik, Tomas, et al.
Publicado: (2017)

Cellularity and Adipogenic Profile of the Abdominal Subcutaneous Adipose Tissue From Obese Adolescents: Association With Insulin Resistance and Hepatic Steatosis
por: Kursawe, Romy, et al.
Publicado: (2010)

Intergenerational Transmission of Glucose Intolerance and Obesity by In Utero Undernutrition in Mice
por: Jimenez-Chillaron, Josep C., et al.
Publicado: (2009)

Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight
por: Sisley, Stephanie R., et al.
Publicado: (2016)

Pregnancy Insulin, Glucose, and BMI Contribute to Birth Outcomes in Nondiabetic Mothers
por: Ong, Ken K., et al.
Publicado: (2008)

Insulin Administration and Rate of Glucose Appearance in People With Type 1 Diabetes
por: Pennant, Mary E., et al.
Publicado: (2008)

Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes
por: Huang-Doran, Isabel, et al.
Publicado: (2011)

Identification of Novel Changes in Human Skeletal Muscle Proteome After Roux-en-Y Gastric Bypass Surgery
por: Campbell, Latoya E., et al.
Publicado: (2016)

Impaired Glucose Tolerance in the Absence of Adenosine A1 Receptor Signaling
por: Faulhaber-Walter, Robert, et al.
Publicado: (2011)

Insulin Resistance Is Associated With Reduced Mitochondrial Oxidative Capacity Measured by (31)P-Magnetic Resonance Spectroscopy in Participants Without Diabetes From the Baltimore Longitudinal Study of Aging
por: Fabbri, Elisa, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jelpjnn7vieahqsg79p456v4q3