Deficiency of Nuclear Factor-κB c-Rel Accelerates the Development of Autoimmune Diabetes in NOD Mice

The nuclear factor-κB protein c-Rel plays a critical role in controlling autoimmunity. c-Rel–deficient mice are resistant to streptozotocin-induced diabetes, a drug-induced model of autoimmune diabetes. We generated c-Rel–deficient NOD mice to examine the role of c-Rel in the development of spontane...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramakrishnan, Parameswaran, Yui, Mary A., Tomalka, Jeffrey A., Majumdar, Devdoot, Parameswaran, Reshmi, Baltimore, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955991/
https://www.ncbi.nlm.nih.gov/pubmed/27217485
http://dx.doi.org/10.2337/db15-1607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955991/
https://www.ncbi.nlm.nih.gov/pubmed/27217485
http://dx.doi.org/10.2337/db15-1607

Ejemplares similares