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Deficiency of Nuclear Factor-κB c-Rel Accelerates the Development of Autoimmune Diabetes in NOD Mice

The nuclear factor-κB protein c-Rel plays a critical role in controlling autoimmunity. c-Rel–deficient mice are resistant to streptozotocin-induced diabetes, a drug-induced model of autoimmune diabetes. We generated c-Rel–deficient NOD mice to examine the role of c-Rel in the development of spontane...

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Detalles Bibliográficos
Autores principales:	Ramakrishnan, Parameswaran, Yui, Mary A., Tomalka, Jeffrey A., Majumdar, Devdoot, Parameswaran, Reshmi, Baltimore, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2016
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955991/ https://www.ncbi.nlm.nih.gov/pubmed/27217485 http://dx.doi.org/10.2337/db15-1607

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