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CREB-regulated transcription coactivator 1 enhances CREB-dependent gene expression in spinal cord to maintain the bone cancer pain in mice

BACKGROUND: cAMP response element binding protein (CREB)-dependent gene expression plays an important role in central sensitization. CREB-regulated transcription coactivator 1 (CRTC1) dramatically increases CREB-mediated transcriptional activity. Brain-derived neurotrophic factor, N-methyl-d-asparta...

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Detalles Bibliográficos
Autores principales: Liang, Ying, Liu, Yue, Hou, Bailing, Zhang, Wei, Liu, Ming, Sun, Yu-E, Ma, Zhengliang, Gu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955996/
https://www.ncbi.nlm.nih.gov/pubmed/27060162
http://dx.doi.org/10.1177/1744806916641679