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D-serine in the midbrain periaqueductal gray contributes to morphine tolerance in rats
BACKGROUND: The N-methyl-D-aspartate subtype of glutamate receptor plays a critical role in morphine tolerance. D-serine, a co-agonist of N-methyl-D-aspartate receptor, participates in many physiological and pathophysiological processes via regulating N-methyl-D-aspartate receptor activation. The pu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956000/ https://www.ncbi.nlm.nih.gov/pubmed/27175014 http://dx.doi.org/10.1177/1744806916646786 |