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D-serine in the midbrain periaqueductal gray contributes to morphine tolerance in rats

BACKGROUND: The N-methyl-D-aspartate subtype of glutamate receptor plays a critical role in morphine tolerance. D-serine, a co-agonist of N-methyl-D-aspartate receptor, participates in many physiological and pathophysiological processes via regulating N-methyl-D-aspartate receptor activation. The pu...

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Detalles Bibliográficos
Autores principales: Cao, Song, Xiao, Zhi, Sun, Mengjie, Li, Youyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956000/
https://www.ncbi.nlm.nih.gov/pubmed/27175014
http://dx.doi.org/10.1177/1744806916646786