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Downregulation of Cdh1 signalling in spinal dorsal horn contributes to the maintenance of mechanical allodynia after nerve injury in rats

BACKGROUND: Anaphase-promoting complex/cyclosome (APC/C) and its co-activator Cdh1 are important ubiquitin-ligases in proliferating cells and terminally differentiated neurons. In recent years, APC/C-Cdh1 has been reported as an important complex contributing to synaptic development and transmission...

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Detalles Bibliográficos
Autores principales: Hu, Rong, Li, Li, Li, Dajia, Tan, Wei, Wan, Li, Zhu, Chang, Zhang, Yue, Zhang, Chuanhan, Yao, Wenlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956001/
https://www.ncbi.nlm.nih.gov/pubmed/27184142
http://dx.doi.org/10.1177/1744806916647376