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Methylcobalamin ameliorates neuropathic pain induced by vincristine in rats: Effect on loss of peripheral nerve fibers and imbalance of cytokines in the spinal dorsal horn

BACKGROUND: Vincristine, a widely used chemotherapeutic agent, often induces painful peripheral neuropathy and there are currently no effective drugs to prevent or treat this side effect. Previous studies have shown that methylcobalamin has potential analgesic effect in diabetic and chronic compress...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Wang, Wei, Zhong, Xiong-Xiong, Feng, Yi-Wei, Wei, Xu-Hong, Liu, Xian-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956006/
https://www.ncbi.nlm.nih.gov/pubmed/27306413
http://dx.doi.org/10.1177/1744806916657089