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Activation of Molecular Signatures for Antimicrobial and Innate Defense Responses in Skin with Transglutaminase 1 Deficiency

Mutations of the transglutaminase 1 gene (TGM1) are a major cause of autosomal recessive congenital ichthyoses (ARCIs) that are associated with defects in skin barrier structure and function. However, the molecular processes induced by the transglutaminase 1 deficiency are not fully understood. The...

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Detalles Bibliográficos
Autores principales: Haneda, Takashi, Imai, Yasutomo, Uchiyama, Ryosuke, Jitsukawa, Orie, Yamanishi, Kiyofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956052/
https://www.ncbi.nlm.nih.gov/pubmed/27442430
http://dx.doi.org/10.1371/journal.pone.0159673