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Sustained Delivery of Bioactive GDNF from Collagen and Alginate-Based Cell-Encapsulating Gel Promoted Photoreceptor Survival in an Inherited Retinal Degeneration Model

Encapsulated-cell therapy (ECT) is an attractive approach for continuously delivering freshly synthesized therapeutics to treat sight-threatening posterior eye diseases, circumventing repeated invasive intravitreal injections and improving local drug availability clinically. Composite collagen-algin...

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Detalles Bibliográficos
Autores principales: Wong, Francisca S. Y., Wong, Calvin C. H., Chan, Barbara P., Lo, Amy C. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956057/
https://www.ncbi.nlm.nih.gov/pubmed/27441692
http://dx.doi.org/10.1371/journal.pone.0159342