Generation of Two Noradrenergic-Specific Dopamine-Beta-Hydroxylase-FLPo Knock-In Mice Using CRISPR/Cas9-Mediated Targeting in Embryonic Stem Cells

CRISPR/Cas9 mediated DNA double strand cutting is emerging as a powerful approach to increase rates of homologous recombination of large targeting vectors, but the optimization of parameters, equipment and expertise required remain barriers to successful mouse generation by single-step zygote inject...

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Detalles Bibliográficos
Autores principales: Sun, Jenny J., Ray, Russell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956144/
https://www.ncbi.nlm.nih.gov/pubmed/27441631
http://dx.doi.org/10.1371/journal.pone.0159474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956144/
https://www.ncbi.nlm.nih.gov/pubmed/27441631
http://dx.doi.org/10.1371/journal.pone.0159474

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