Functional inhibition of chemokine receptor CCR2 by dicer-substrate-siRNA prevents pain development

BACKGROUND: Accumulating evidence suggests that the C-C chemokine ligand 2 (CCL2, or monocyte chemoattractant protein 1) acts as a neuromodulator in the central nervous system through its binding to the C-C chemokine receptor 2 (CCR2). Notably, it is well established that the CCL2/CCR2 axis plays a...

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Detalles Bibliográficos
Autores principales: Bégin-Lavallée, Valérie, Midavaine, Élora, Dansereau, Marc-André, Tétreault, Pascal, Longpré, Jean-Michel, Jacobi, Ashley M, Rose, Scott D, Behlke, Mark A, Beaudet, Nicolas, Sarret, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956154/
https://www.ncbi.nlm.nih.gov/pubmed/27306408
http://dx.doi.org/10.1177/1744806916653969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956154/
https://www.ncbi.nlm.nih.gov/pubmed/27306408
http://dx.doi.org/10.1177/1744806916653969

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