A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase

Fatty-acid amide hydrolase (FAAH) is the major enzyme responsible for degradation of anandamide, an endocannabinoid. Pharmacological inhibition or genetic deletion of FAAH (FAAH KO) produces antinociception in preclinical pain models that is largely attributed to anandamide-induced activation of can...

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Detalles Bibliográficos
Autores principales: Carey, Lawrence M, Slivicki, Richard A, Leishman, Emma, Cornett, Ben, Mackie, Ken, Bradshaw, Heather, Hohmann, Andrea G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956176/
https://www.ncbi.nlm.nih.gov/pubmed/27178246
http://dx.doi.org/10.1177/1744806916649192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956176/
https://www.ncbi.nlm.nih.gov/pubmed/27178246
http://dx.doi.org/10.1177/1744806916649192

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