Inhibition of the Unfolded Protein Response Mechanism Prevents Cardiac Fibrosis

BACKGROUND: Cardiac fibrosis attributed to excessive deposition of extracellular matrix proteins is a major cause of heart failure and death. Cardiac fibrosis is extremely difficult and challenging to treat in a clinical setting due to lack of understanding of molecular mechanisms leading to cardiac...

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Detalles Bibliográficos
Autores principales: Groenendyk, Jody, Lee, Dukgyu, Jung, Joanna, Dyck, Jason R. B., Lopaschuk, Gary D., Agellon, Luis B., Michalak, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956237/
https://www.ncbi.nlm.nih.gov/pubmed/27441395
http://dx.doi.org/10.1371/journal.pone.0159682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956237/
https://www.ncbi.nlm.nih.gov/pubmed/27441395
http://dx.doi.org/10.1371/journal.pone.0159682

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