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Generation and Characterization of a Bivalent HIV-1 Subtype C gp120 Protein Boost for Proof-of-Concept HIV Vaccine Efficacy Trials in Southern Africa

The viral envelope glycoprotein (Env) is the major target for antibody (Ab)-mediated vaccine development against the Human Immunodeficiency Virus type 1 (HIV-1). Although several recombinant Env antigens have been evaluated in clinical trials, only the surface glycoprotein, gp120, (from HIV-1 subtyp...

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Detalles Bibliográficos
Autores principales: Zambonelli, Carlo, Dey, Antu K., Hilt, Susan, Stephenson, Samuel, Go, Eden P., Clark, Daniel F., Wininger, Mark, Labranche, Celia, Montefiori, David, Liao, Hua-Xin, Swanstrom, Ronald I., Desaire, Heather, Haynes, Barton F., Carfi, Andrea, Barnett, Susan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956256/
https://www.ncbi.nlm.nih.gov/pubmed/27442017
http://dx.doi.org/10.1371/journal.pone.0157391