Efficacy Coefficients Determined Using Nail Permeability and Antifungal Activity in Keratin-Containing Media Are Useful for Predicting Clinical Efficacies of Topical Drugs for Onychomycosis

Onychomycosis is difficult to treat topically due to the deep location of the infection under the densely keratinized nail plate. In order to obtain an in vitro index that is relevant to the clinical efficacy of topical anti-onychomycosis drugs, we profiled five topical drugs: amorolfine, ciclopirox...

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Detalles Bibliográficos
Autores principales: Matsuda, Yoshiki, Sugiura, Keita, Hashimoto, Takashi, Ueda, Akane, Konno, Yoshihiro, Tatsumi, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956321/
https://www.ncbi.nlm.nih.gov/pubmed/27441843
http://dx.doi.org/10.1371/journal.pone.0159661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956321/
https://www.ncbi.nlm.nih.gov/pubmed/27441843
http://dx.doi.org/10.1371/journal.pone.0159661

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