Interferon-gamma potentiates NMDA receptor signaling in spinal dorsal horn neurons via microglia–neuron interaction

BACKGROUND: Glia–neuron interactions play an important role in the development of neuropathic pain. Expression of the pro-inflammatory cytokne →cytokine Interferon-gamma (IFNγ) is upregulated in the dorsal horn after peripheral nerve injury, and intrathecal IFNγ administration induces mechanical all...

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Detalles Bibliográficos
Autores principales: Sonekatsu, Mayumi, Taniguchi, Wataru, Yamanaka, Manabu, Nishio, Naoko, Tsutsui, Shunji, Yamada, Hiroshi, Yoshida, Munehito, Nakatsuka, Terumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956380/
https://www.ncbi.nlm.nih.gov/pubmed/27094552
http://dx.doi.org/10.1177/1744806916644927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956380/
https://www.ncbi.nlm.nih.gov/pubmed/27094552
http://dx.doi.org/10.1177/1744806916644927

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