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Interferon-gamma potentiates NMDA receptor signaling in spinal dorsal horn neurons via microglia–neuron interaction
BACKGROUND: Glia–neuron interactions play an important role in the development of neuropathic pain. Expression of the pro-inflammatory cytokne →cytokine Interferon-gamma (IFNγ) is upregulated in the dorsal horn after peripheral nerve injury, and intrathecal IFNγ administration induces mechanical all...
Autores principales: | Sonekatsu, Mayumi, Taniguchi, Wataru, Yamanaka, Manabu, Nishio, Naoko, Tsutsui, Shunji, Yamada, Hiroshi, Yoshida, Munehito, Nakatsuka, Terumasa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956380/ https://www.ncbi.nlm.nih.gov/pubmed/27094552 http://dx.doi.org/10.1177/1744806916644927 |
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