Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse

T cell receptor (TCR) engagement opens Ca(2+) release-activated Ca(2+) (CRAC) channels and triggers formation of an immune synapse between T cells and antigen-presenting cells. At the synapse, actin reorganizes into a concentric lamellipod and lamella with retrograde actin flow that helps regulate t...

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Detalles Bibliográficos
Autores principales: Hartzell, Catherine A, Jankowska, Katarzyna I, Burkhardt, Janis K, Lewis, Richard S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956410/
https://www.ncbi.nlm.nih.gov/pubmed/27440222
http://dx.doi.org/10.7554/eLife.14850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956410/
https://www.ncbi.nlm.nih.gov/pubmed/27440222
http://dx.doi.org/10.7554/eLife.14850

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