Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F

The human APOBEC3 family of DNA cytosine deaminases serves as a front-line intrinsic immune response to inhibit the replication of diverse retroviruses. APOBEC3F and APOBEC3G are the most potent factors against HIV-1. As a countermeasure, HIV-1 viral infectivity factor (Vif) targets APOBEC3s for pro...

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Detalles Bibliográficos
Autores principales: Siu, Karen K., Sultana, Azmiri, Azimi, Farshad C., Lee, Jeffrey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956467/
https://www.ncbi.nlm.nih.gov/pubmed/24185281
http://dx.doi.org/10.1038/ncomms3593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956467/
https://www.ncbi.nlm.nih.gov/pubmed/24185281
http://dx.doi.org/10.1038/ncomms3593

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