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Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F
The human APOBEC3 family of DNA cytosine deaminases serves as a front-line intrinsic immune response to inhibit the replication of diverse retroviruses. APOBEC3F and APOBEC3G are the most potent factors against HIV-1. As a countermeasure, HIV-1 viral infectivity factor (Vif) targets APOBEC3s for pro...
Autores principales: | Siu, Karen K., Sultana, Azmiri, Azimi, Farshad C., Lee, Jeffrey E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956467/ https://www.ncbi.nlm.nih.gov/pubmed/24185281 http://dx.doi.org/10.1038/ncomms3593 |
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