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GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis

To identify genes and biologically relevant pathways associated with risk to develop multiple sclerosis (MS), the Genome-Wide Association Studies noise reduction method (GWAS-NR) was applied to MS genotyping data. Regions of association were defined based on the significance of linkage disequilibriu...

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Detalles Bibliográficos
Autores principales: Hussman, J P, Beecham, A H, Schmidt, M, Martin, E R, McCauley, J L, Vance, J M, Haines, J L, Pericak-Vance, M A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956564/
https://www.ncbi.nlm.nih.gov/pubmed/27278126
http://dx.doi.org/10.1038/gene.2016.23