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Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus during Social or Psychological Stress in Mice

Hypothalamic oxytocin (OT) is released into the brain by cyclic ADP-ribose (cADPR) with or without depolarizing stimulation. Previously, we showed that the intracellular free calcium concentration ([Ca(2+)](i)) that seems to trigger OT release can be elevated by β-NAD(+), cADPR, and ADP in mouse oxy...

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Detalles Bibliográficos
Autores principales: Zhong, Jing, Amina, Sarwat, Liang, Mingkun, Akther, Shirin, Yuhi, Teruko, Nishimura, Tomoko, Tsuji, Chiharu, Tsuji, Takahiro, Liu, Hong-Xiang, Hashii, Minako, Furuhara, Kazumi, Yokoyama, Shigeru, Yamamoto, Yasuhiko, Okamoto, Hiroshi, Zhao, Yong Juan, Lee, Hon Cheung, Tominaga, Makoto, Lopatina, Olga, Higashida, Haruhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956647/
https://www.ncbi.nlm.nih.gov/pubmed/27499729
http://dx.doi.org/10.3389/fnins.2016.00304