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An Adaptive Defect Weighted Sampling Algorithm to Design Pseudoknotted RNA Secondary Structures

Computational design of RNA sequences that fold into targeted secondary structures has many applications in biomedicine, nanotechnology and synthetic biology. An RNA molecule is made of different types of secondary structure elements and an important RNA element named pseudoknot plays a key role in...

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Detalles Bibliográficos
Autores principales: Zandi, Kasra, Butler, Gregory, Kharma, Nawwaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956659/
https://www.ncbi.nlm.nih.gov/pubmed/27499762
http://dx.doi.org/10.3389/fgene.2016.00129