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Assessing the reliability of uptake and elimination kinetics modelling approaches for estimating bioconcentration factors in the freshwater invertebrate, Gammarus pulex

This study considers whether the current standard toxicokinetic methods are an accurate and applicable assessment of xenobiotic exposure in an aquatic freshwater invertebrate. An in vivo exposure examined the uptake and elimination kinetics for eight pharmaceutical compounds in the amphipod crustace...

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Detalles Bibliográficos
Autores principales: Miller, Thomas H., McEneff, Gillian L., Stott, Lucy C., Owen, Stewart F., Bury, Nicolas R., Barron, Leon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956724/
https://www.ncbi.nlm.nih.gov/pubmed/26789375
http://dx.doi.org/10.1016/j.scitotenv.2015.12.145