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Assessing the reliability of uptake and elimination kinetics modelling approaches for estimating bioconcentration factors in the freshwater invertebrate, Gammarus pulex
This study considers whether the current standard toxicokinetic methods are an accurate and applicable assessment of xenobiotic exposure in an aquatic freshwater invertebrate. An in vivo exposure examined the uptake and elimination kinetics for eight pharmaceutical compounds in the amphipod crustace...
Autores principales: | Miller, Thomas H., McEneff, Gillian L., Stott, Lucy C., Owen, Stewart F., Bury, Nicolas R., Barron, Leon P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956724/ https://www.ncbi.nlm.nih.gov/pubmed/26789375 http://dx.doi.org/10.1016/j.scitotenv.2015.12.145 |
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