Serotonin biosynthesis as a predictive marker of serotonin pharmacodynamics and disease-induced dysregulation

The biogenic amine serotonin (5-HT) is a multi-faceted hormone that is synthesized from dietary tryptophan with the rate limiting step being catalyzed by the enzyme tryptophan hydroxylase (TPH). The therapeutic potential of peripheral 5-HT synthesis inhibitors has been demonstrated in a number of cl...

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Detalles Bibliográficos
Autores principales: Welford, Richard W. D., Vercauteren, Magali, Trébaul, Annette, Cattaneo, Christophe, Eckert, Doriane, Garzotti, Marco, Sieber, Patrick, Segrestaa, Jérôme, Studer, Rolf, Groenen, Peter M. A., Nayler, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956766/
https://www.ncbi.nlm.nih.gov/pubmed/27444653
http://dx.doi.org/10.1038/srep30059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956766/
https://www.ncbi.nlm.nih.gov/pubmed/27444653
http://dx.doi.org/10.1038/srep30059

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