Inhibition of Rac1 reduces store overload‐induced calcium release and protects against ventricular arrhythmia

Rac1 is a small GTPase and plays key roles in multiple cellular processes including the production of reactive oxygen species (ROS). However, whether Rac1 activation during myocardial ischaemia and reperfusion (I/R) contributes to arrhythmogenesis is not fully understood. We aimed to study the effec...

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Detalles Bibliográficos
Autores principales: Zhang, Lili, Lu, Xiangru, Gui, Le, Wu, Yan, Sims, Stephen M., Wang, Guoping, Feng, Qingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956946/
https://www.ncbi.nlm.nih.gov/pubmed/27222313
http://dx.doi.org/10.1111/jcmm.12840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956946/
https://www.ncbi.nlm.nih.gov/pubmed/27222313
http://dx.doi.org/10.1111/jcmm.12840

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