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Shared mechanism of teratogenicity of anti-angiogenic drugs identified in the chicken embryo model

Angiogenesis, the formation of new blood vessels, is essential for tumor growth, stabilization and progression. Angiogenesis inhibitors are now widely used in the clinic; however, there are relatively few published studies on the mechanism of their presumed teratogenic effects. To address this issue...

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Detalles Bibliográficos
Autores principales: Beedie, Shaunna L., Mahony, Chris, Walker, Heather M., Chau, Cindy H., Figg, William D., Vargesson, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957076/
https://www.ncbi.nlm.nih.gov/pubmed/27443489
http://dx.doi.org/10.1038/srep30038