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Shared mechanism of teratogenicity of anti-angiogenic drugs identified in the chicken embryo model
Angiogenesis, the formation of new blood vessels, is essential for tumor growth, stabilization and progression. Angiogenesis inhibitors are now widely used in the clinic; however, there are relatively few published studies on the mechanism of their presumed teratogenic effects. To address this issue...
Autores principales: | Beedie, Shaunna L., Mahony, Chris, Walker, Heather M., Chau, Cindy H., Figg, William D., Vargesson, Neil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957076/ https://www.ncbi.nlm.nih.gov/pubmed/27443489 http://dx.doi.org/10.1038/srep30038 |
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