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miR-877-3p targets Smad7 and is associated with myofibroblast differentiation and bleomycin-induced lung fibrosis

Myofibroblast differentiation of lung resident mesenchymal stem cells (LR-MSC) plays an important role in idiopathic pulmonary fibrosis. By comparing the expression profiles of miRNAs before and after myofibroblast differentiation of LR-MSC, we identified miR-877-3p as a fibrosis-related miRNA. We f...

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Detalles Bibliográficos
Autores principales: Wang, Cong, Gu, Shen, Cao, Honghui, Li, Zutong, Xiang, Zou, Hu, Kebin, Han, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957095/
https://www.ncbi.nlm.nih.gov/pubmed/27444321
http://dx.doi.org/10.1038/srep30122