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Metabolomics analysis for hydroxy-L-proline-induced calcium oxalate nephrolithiasis in rats based on ultra-high performance liquid chromatography quadrupole time-of-flight mass spectrometry

About 80% of kidney stones are composed of calcium oxalate (CaOx) with variable amounts of calcium phosphate, and hyperoxaluria is considered as an important factor of CaOx nephrolithiasis. However, the underlying metabolic mechanisms of CaOx nephrolithiasis remain undefined. In this study, we succe...

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Detalles Bibliográficos
Autores principales: Gao, Songyan, Yang, Rui, Peng, Zhongjiang, Lu, Hongtao, Li, Na, Ding, Jiarong, Cui, Xingang, Chen, Wei, Dong, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957101/
https://www.ncbi.nlm.nih.gov/pubmed/27443631
http://dx.doi.org/10.1038/srep30142