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Discovery of Nigri/nox and Panto/pox site-specific recombinase systems facilitates advanced genome engineering

Precise genome engineering is instrumental for biomedical research and holds great promise for future therapeutic applications. Site-specific recombinases (SSRs) are valuable tools for genome engineering due to their exceptional ability to mediate precise excision, integration and inversion of genom...

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Detalles Bibliográficos
Autores principales: Karimova, Madina, Splith, Victoria, Karpinski, Janet, Pisabarro, M. Teresa, Buchholz, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957104/
https://www.ncbi.nlm.nih.gov/pubmed/27444945
http://dx.doi.org/10.1038/srep30130