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Mesenchymal progenitors in osteopenias of diverse pathologies: differential characteristics in the common shift from osteoblastogenesis to adipogenesis

Osteoporosis is caused by pathologic factors such as aging, hormone deficiency or excess, inflammation, and systemic diseases like diabetes. Bone marrow stromal cells (BMSCs), the mesenchymal progenitors for both osteoblasts and adipocytes, are modulated by niche signals. In differential pathologic...

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Detalles Bibliográficos
Autores principales: Sui, Bingdong, Hu, Chenghu, Liao, Li, Chen, Yichen, Zhang, Xinyi, Fu, Xin, Zheng, Chenxi, Li, Meng, Wu, Ling, Zhao, Xinyi, Jin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957106/
https://www.ncbi.nlm.nih.gov/pubmed/27443833
http://dx.doi.org/10.1038/srep30186