Impact of structural polymorphism for the Helicobacter pylori CagA oncoprotein on binding to polarity-regulating kinase PAR1b

Chronic infection with cagA-positive Helicobacter pylori is the strongest risk factor for atrophic gastritis, peptic ulcers, and gastric cancer. CagA, the product of the cagA gene, is a bacterial oncoprotein, which, upon delivery into gastric epithelial cells, binds to and inhibits the polarity-regu...

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Detalles Bibliográficos
Autores principales: Nishikawa, Hiroko, Hayashi, Takeru, Arisaka, Fumio, Senda, Toshiya, Hatakeyama, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957108/
https://www.ncbi.nlm.nih.gov/pubmed/27445265
http://dx.doi.org/10.1038/srep30031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957108/
https://www.ncbi.nlm.nih.gov/pubmed/27445265
http://dx.doi.org/10.1038/srep30031

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