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Dysfunctional epileptic neuronal circuits and dysmorphic dendritic spines are mitigated by platelet-activating factor receptor antagonism

Temporal lobe epilepsy or limbic epilepsy lacks effective therapies due to a void in understanding the cellular and molecular mechanisms that set in motion aberrant neuronal network formations during the course of limbic epileptogenesis (LE). Here we show in in vivo rodent models of LE that the phos...

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Detalles Bibliográficos
Autores principales: Musto, Alberto E., Rosencrans, Robert F., Walker, Chelsey P., Bhattacharjee, Surjyadipta, Raulji, Chittalsinh M., Belayev, Ludmila, Fang, Zhide, Gordon, William C., Bazan, Nicolas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957208/
https://www.ncbi.nlm.nih.gov/pubmed/27444269
http://dx.doi.org/10.1038/srep30298